CN239408[trait identifier] AND "Illumina Laboratory Services, Illumina - ClinVar

	Variation	Gene (Protein Change)	Type (Consequence)	Condition	Classification, Review status
Select item 1245	NM_024675.4(PALB2):c.3549C>G (p.Tyr1183Ter)	PALB2 (Y1183*)	Single nucleotide variant (nonsense)	Hereditary cancer-predisposing syndrome +4 more	GPathogenic/Likely pathogenic
Select item 126729	NM_024675.4(PALB2):c.3256C>T (p.Arg1086Ter)	PALB2 (R1086*)	Single nucleotide variant (nonsense)	Breast-ovarian cancer, familial, susceptibility to, 5 +9 more	GPathogenic/Likely pathogenic
Select item 143972	NM_024675.4(PALB2):c.3201+1G>C	PALB2	Single nucleotide variant (intron variant +1 more)	not provided +3 more	GConflicting classifications of pathogenicity
Select item 126711	NM_024675.4(PALB2):c.3113G>A (p.Trp1038Ter)	PALB2 (W1038*)	Single nucleotide variant (nonsense)	Familial cancer of breast	GPathogenic FDA Recognized database
Select item 410213	NM_024675.4(PALB2):c.1553C>G (p.Ser518Ter)	PALB2 (S518*)	Single nucleotide variant (nonsense)	Familial cancer of breast +2 more	GPathogenic
Select item 126769	NM_024675.4(PALB2):c.758dup (p.Ser254fs)	PALB2 (S254fs)	Duplication (frameshift variant)	not provided +6 more	GPathogenic/Likely pathogenic
Select item 126757	NM_024675.4(PALB2):c.509_510del (p.Arg170fs)	PALB2	Deletion (frameshift variant)	Breast-ovarian cancer, familial, susceptibility to, 1 +11 more	GPathogenic

ClinVar